An FDA-approved Irreversible Time and Temperature Indicator that ensures that only viable whole blood supplies are used post-transit
The high tech, low cost alternative to electronic dataloggers
Delivery of unambiguous safety data
Ease of use
Low carbon footprint
critical issue for medical professionals is ensuring the viability of blood
supplies once they leave the highly controlled storage environment, such as a
blood bank refrigerator or
a hospital blood storage facility. This aspect of the so-called blood
cold chain is essential for ensuring that these are kept at the correct
temperature right up to the time they are administered by trauma units,
ERs, operating theatre staff, air/ ground ambulances, and any other situation
requiring blood to be transported from storage units out to patients.
During transit, whole blood needs to be
kept within a temperature range of 2°C/36OF
Below this range, there is a risk of freezing with the formation of ice
crystals, rendering the blood unusable, while upper temperature breaches create
the possibility of blood being affected by an overgrowth of non-specific
bacteria, which may have entered the blood unit during collection or component
Both these situations have serious
consequences: the cost implications of a wasted product and/or more seriously,
a patient that is put at risk.
To address these issues, Timestrip® has
developed its single-use Blood Temp 10 – a high-tech, low cost Irreversible
Time & Temperature Indicator that effectively monitors temperature breaches
above 10°C/50°F during transit.
No more guesswork
Thanks to its innovative technology,
Timestrip® Blood Temp 10 removes this uncertainty by providing clear,
unambiguous data as to whether a supply of whole blood is safe to use or be
returned to storage.
This is achieved thanks to the smart
label’s two indicator windows:
• the first window to indicate if the
label has been activated
• the second to indicate if a temperature
breach has occurred
Thus, at a glance, medical staff know if
a supply of whole blood is not only safe to use post-transit. The smart label
also ensures a higher level of quality of the product is delivered by
monitoring of temperature throughout transit.
Moreover, thanks to its irreversible feature,
once the smart label has reacted to a temperature breach, this cannot be
undone. For security reasons, the colour of the label’s indicator window stays
FDA approved … and more
Timestrip® Blood Temp 10 has FDA
certification (FDA 510(k) #BK190363)
manufactured with controls established by a IQC approved quality management system that
conforms with ISO 9001:2015 and ISO 13485:2016.
With a temperature accuracy of +/- 0.5°C,
this means that the Timestrip® label is designed with reliable and, more
importantly, trustworthy technology as assessed by some of the world’s most
stringent criteria. Moreover, extra security is assured by every Timestrip®
label having its own unique serial number, thus ensuring full traceability.
Checking this list of features brings
further benefits to healthcare providers involved in the transportation of
whole blood by also ticking the box for local and internal regulatory
Because Timestrip® Blood Temp 10 ensures
that only viable blood supplies are either administered post-transit, or
returned to storage, the possibility of precautionary disposal is eliminated.
This reduction in waste can have significant cost benefits.
In fact, studies
have shown that loss rates without a Timestrip® are around 5%. These are halved with its use. In fact,
reducing a loss rate by 9.9% pays for the total investment and a conservative
19.8% reduction doubles the ROI.
generation of similar positive temperature monitoring outcomes are possible
using other products, such as electronic devices. These, however, are far
Ease of use
Apart from delivering clear, unambiguous data as to
whether post-transit a unit of whole blood may be used or returned to storage
thanks its innovative indicator windows, the Timestrip® Blood Temp 10 is also
remarkably easy to use.
In fact, unlike other whole blood temperature
monitoring solutions on the market, Timestrip® Blood Temp 10 is a unique FDA
510(k) medical device that does not require preconditioning. Moreover, it is
also CE approved and designed for:
• quick and easy application
• no prior conditioning by blood storage staff
• temperature breach data delivered at a glance by
medical field personnel.
Prior to the transit of a unit of whole blood, a
simple squeeze of the label’s activation blister is all that is required for
temperature monitoring of a unit of whole blood to begin. Then the label just
needs to stuck on the unit.
Squeeze, peel and stick – that’s it!
And the end of transit, Timestrip® technology has
also been designed for maximum ease of use:
• until activation, the first indicator window is
yellow and the second is white
• upon activation, the first indicator window turns
• if a temperature breach has occurred during transit, the duration of the breach is indicated by the second white indicator window that proportionately fills up with blue dye
Irreversible, single use
19mm x 32mm
Visual proof of temperature exposure
Advantages over electronic dataloggers
being less expensive, Timestrip® Blood Temp 10 does not involve a datalogger’s
complicated and sometimes cumbersome unit return program that is necessary to
make it more affordable. The smart label’s single use indicator makes it the
ideal fit for simple, straightforward and effective temperature monitoring.
Timestrip® also is a super convenient shape: small, flat, with no batteries or
any other electronic components to them.
green credentials, the Timestrip® also outstrips traditional dataloggers in
terms of carbon footprint, because the latter eventually needs to be either be
thrown away or sent back to source to justify the expenditure.
the Timestrip® has the potential of generating more accurate safety data.
Indeed, because a container of units of whole blood will tend to use just a
single datalogger, inevitably the temperature of ambient air within the
container is taken into account, potentially generating less than accurate
Timestrip® labels however, every single unit has its own temperature indicator.
This means that the possibility of rejecting an entire shipment based on a
single result is eliminated.
adminTimestrip Blood Temp 10: less waste, lower cost, less risk
Timestrip will be attending the 29th Regional Congress of the International Society of Blood Transfusion (ISBT) in Basel, Switzerland from 22nd – 26th June 2019
We will demonstrate our Timestrip® Blood Temp 10 and Timestrip® Blood Temp 6 at the exhibition. We will be at Booth U106, Hall 4.U, please drop by and get a sample of our Blood Temp indicators to take away with you.
Our Blood Temp irreversible blood bag temperature indicators monitor temperature compliance in blood bags. They are especially relevant for monitoring blood temperature during transit from the highly controlled environment of the blood bank to use or store in a different destination, such as a hospital.
ISBT is a society in the field of blood transfusion, transplants, science and medicine. It facilitates knowledge about transfusion medicine to serve the interests of donors and patients.
Wine has always been a popular drink and
for many the fermented beverage of choice. In most cases whether you prefer Red
or White, or even a Rose, experts and connoisseurs believe that any wine is
best stored and served chilled.
So, you may well ask what is the difference
between a wine served warm, or chilled, and does it really matter if the wine
is warmer than expected, or even hot? Some wines are indeed served hot and are
even used in cooking, but why is it important if it gets hotter than
anticipated before it gets to the consumer?
Well, from an article in WinePair ™ a short time ago it was stated that; wines do change when they are subjected to a high temperature. Firstly, the tannins become ‘more noticeable and wines take on a tangy, astringent character. Instead of a smooth and supple mouthfeel, wines feel rough and more one-note on the palate. Fruit flavors often become secondary to unpleasant acidity. In dry climates, corks shrink as they lose moisture, leading to leaky bottles and a sticky mess.’
This is all well and good, but at above
what temperature would there be any noticeable change to the wine we drink?
Any wine should normally be stored between 55 – 65F (13-18C) and wine should be stored in a cellar, or a wine refrigerator, that maintains this recommended temperature level. And, it is generally noted that the change to the body of the wine begins at 70F (21C), and wines can “cook” as exposure temperatures hit 80F (26C) degrees and beyond. However, an occasional spike won’t decimate a wine, but prolonged exposure — like a week-long heat wave, or full day in the car — can.
Timestrip offers a full range of stock
labels including two that have a temperature breach of 20C and 25C (tolerance
+/- 1C), and Timestrip can also produce a custom and branded label that can be
set to monitor more specific temperature breach limits.
So, in the future be on the look out for
some form of temperature indicator label on the bottle of wine that you buy to
ensure that it has been kept at the recommended temperature to insure you get
the most enjoyment from the wine that you buy and drink.
How Timestrip irreversible time sensitive indicators are used in Germany by Ulmer Wohnungs for their apartment ventilation units to remind tenants that they need to change the ventilation duct filters.
Translation: “In many UWS apartments, ventilation units are installed which permanently ensure fresh and clean air. Only when the filter is clean, do the fans work quietly and use less energy. In our video we show you how to easily change the filter.”
Timestrip can make you a custom Time Sensitive Indicator Label – we create custom solutions that measure time ranging from 1 hour up to 2 years. We are ISO 9001:2015 certified and Timestrip time indicators offer a helpful visual reminder of service and maintenance schedules for consumable components. Accurate and reliable, Timestrips contribute to a more positive experience for the consumer and help ensure optimum performance from appliances that need replacement indicators or service reminder indicators in order to function effectively.
adminTimestrip Irreversible Time Sensitive Labels used by Ulmer Wohnungs for Filter change Reminders
There are many ways to measure temperature change and for recording how long a temperature-controlled substance, material, or chemical compound, is maintained outside of its normal required temperature limits for stability, or future use. Time Out is not a new term, or monitoring application, but it is a complex one and certainly needed. The most common is for Pre-Preg and Carbon Fiber materials that must be maintained within strict temperature guidelines for flexibility and strength requirements, plus many Chemical compounds and liquid API’s (Active Pharmaceutical Ingredients). These strict limits also apply to certain bio-logics and vaccines that can only be “out-of-environment” for short periods of time whilst they are being worked with, formulated, or packaged.
These tracking solutions range from RFID tracking and monitoring with expensive tags and readers to complex solution software applications that read and record these expensive electronic devices, attached to the item being monitored, as these pass in and out of the safe temperature zones.
On the low-end monitoring is done by timers with alarms and some form of temperature recorder to show the temperature limits that the materials were exposed to. Combine both elements and you get a Time and Temperature limit that the materials were within showing how long this was for.
But in some applications, simplicity may be a better solution like – a time and temperature breach indicator label, instead of reading separate items and manually recording these for record purposes.
Timestrip Plus labels and Run Timer Labels are used for many applications ranging from monitoring event times related to an expiration of effect use life to monitoring vaccine and bio’ shipments as these pass through a logistics operation, or down the cold chain supply chain. However, if you take a Timestrip Plus label that contains a time element and a temperature limit indicator for an excursion, or the work environment temperature, you have a truly unique and simple way of measuring TOTCE!
The advantage that these labels offer is quite simple by the fact that once the label is outside of its “strike” temperature the chemical will flow down the time indicator scale to show how long the label is outside of the lower product stability-controlled temperature environment. When the material or chemical substance with the label attached is returned to the temperature-controlled environment the chemical will stop flowing and only now show the “Out-Time”. If this item is taken in and out many times the label will begin to form a total aggregated TOTCE as the chemical flows and stops each time it moves in and out of the two environments.
A record of each individual “Out-Time” can be captured by taking a photo with a Smart Phone which will show the time and date that it was taken, and this can be stored as a permanent record linked to the serial number on the label itself that will be clearly seen in the photograph.
Sometimes simple is the best approach based upon the old adage of the “KISS” philosophy, so contact Timestrip today if you want to find out more about this TOTCE solution offering.
adminTime Out of Temperature Controlled Environment – TOTCE