Timestrip® PLUS Duo

Double action temperature monitoring in one, cost-effective device.

Calibrated to follow WHO recommendations vaccines & medicine, Timestrip® PLUS Duo provides clear, irreversible visual evidence and distinct time marking of the thermal abuse phase for dual temperature thresholds.

Ease of Use

Timestrip® PLUS Duo is inert prior to activation. They can be shipped and stored at ambient temperatures and have no special storage requirements.

Timestrip® PLUS Duo windows are white before activation.

Activate at room temperature, no pre-conditioning is required. Activation is possible only when the surrounding temperature is above the stated threshold temperature.

Clear Activation

Firmly squeeze the blister on the bottom of the indicator.

Once activated, an activation line appears in the first window of the activation windows and continues to fill the window with colour until it reads “ON”.

The Timestrip® PLUS Duo can be directly applied by removing the adhesive liner on the back.


Once activated, Timestrip® PLUS Duo will keep monitoring temperature for days, weeks or months, depending on your needs. 

During that time, it will record how long any temperature breaches last.

Timestrip® PLUS Duo is a cumulative breach indicator with readings for excursions above 10°C – in day ranges from 3 to 14, with a secondary indicator to show immediate excursions above an upper temperature breach point of 34°C.

Breach recordings are irreversible.

Timestrip® PLUS Duo Products

Timestrip® PLUS Duo

for Vaccine, Medicine Storage and Transport

10°C / 50°F 14 day run out

34°C / 93°F immediate excursion

activation blister on bottom

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  • Activation Feature- shipped & stored under any temperature conditions
  • Highly Accurate
  • Activation Confirmation- windows confirm indicator is 'ON'
  • Traceability- unique serial code printed on each indicator
  • Long Shelf Life
  • Unambiguous Colour Progression - shows length of temperature breach
  • Customization - product & carrying cards available to distinguish your brand
  • Modern Look & Feel
  • Environmentally Friendly


Timestrip ISO 9001 certificationOur products are manufactured under the controls established by an IQC approved quality management system that conforms with ISO 9001:2008

In- depth information with push-button simplicity

By removing the ambiguity of temperature abuse across time and temperature thresholds this all-in-one indicator can help prevent the unnecessary wastage of expensive medicines and vaccines.

Timestrip® PLUS Duo indicators are accurate, cost-effective and easy to use and can be directly applied to products and/or packaging.

Custom carrying cards can be produced to enhance your brand.


Type Irreversible, single use
Size 80mm x 19mm
Activation Feature Two manual activation buttons on the back – One for each temperature threshold. Both ‘On’ windows turn green.
Breach Indication Windows A, B, C or D turn blue if thresholds are breached for the time thresholds indicated.
Time / Temp Thresholds A, B, C Threshold of 10°C/50°F and STOP of 8°C/46°F. Time markers; 3 days (A), 8 days (B) and 14 days (C).
Time / Temp Threshold D Threshold of 34°C/93°F and STOP of 30°C/86°F. Time marker; 3 hours.
Temperature Accuracy +/-1°C / 2°F
Time Accuracy +/-15% in isothermal conditions
Recommended Storage Room temperature: 22°C/72°F at 20-80% humidity. Cool dark environment.
Packaging 100 indicators per bag. Labelled with expiry and batch number.
Shipping Package Requirements No special requirements as inert until activated.
Protection Splash proof
Shelf life Pre-activation: 2 years from shipping for most lines, otherwise 2 years from manufacturing date. Active life: up to 1 year.
Quality Assurance Produced under ISO 9001:2015

Frequently Asked Questions

Timestrip Duo

Timestrip® PLUS Duo puts two temperature threshold indicators side by side into one handy label format.
The indicator on the left shows if temperatures have breached the cold chain threshold of 10°C/50°F and for how long, with time markers for 3, 8 or 14 days. The indicator on the right shows if temperatures have breached an extreme of 34°C/93°F and for how long, with one time marker for 3 hours.

Duo has been engineered to comply with World Health Organisation recommended monitoring requirements for certain vaccines. That is why it combines a threshold indicator of 10°C/50°F with 3, 8, and 14 day time markers and a 34°C/93°F indicator showing 3 hours of breach. However, there is nothing to prevent Duo being used to monitor other products if these time markers and threshold temperatures are suitable. It is also possible to manufacture Dual threshold indicators for other temperature thresholds. (See FAQ on customising Duo).

Because we like our customers!

You can use these free products for testing, training, validation, or just to save money. In the unlikely case any got damaged along the way or someone just wanted to try one, there is no need to get in touch, although we’re always happy to hear from our customers.

Personally, we think that all companies should give stuff away for free!

Yes. Orientation has no impact on the way it works.

A blue dye housed in a blister is held adjacent to a micro-porous membrane. Upon squeezing the activation button the liquid dye comes out of the blister and into contact with the membrane.
If the temperature of the product is below the stated ‘STOP’ temperature, the blue dye changes state to solid form, and it is unable to move through the membrane. If the temperature rises to or above the threshold temperature, the dye changes to liquid form and moves at a precise rate through the membrane. Its progress is irreversible and the distance it travels through the viewing window indicates the cumulative time the indicator has been exposed to the threshold temperature or above.
The 10°C and 34°C threshold indicators use different liquid dyes which melt and solidify at different temperatures. The liquid dye in the 10°C blister has a STOP of 8°C/46°F and the liquid dye in the 34°C blister has a STOP of 30°C/86°F.

No. Unlike some other threshold temperature products, Duo indicators do not require pre-conditioning.
However, you need to activate above the highest threshold temperature, as you cannot squeeze the dye out of the blister if it is in solid form.
The temperature of Duo needs to be raised to 35°C/95°F to be able to activate both indicators and then dropped to the lower of the two STOP temperatures (8°C/46°F) to stop the progress of both liquid dyes. The fastest way to do this is by placing Duo in an environment much colder than the STOP temperature (8°C/46°F) for a short period of time.

No, unlike some other threshold temperature products, they can be held at ambient temperatures.

+/- 1˚C for each temperature component and +/- 15% for each time component.
The run rate of the blue dye across the time markers is calibrated to a temperature of 2˚C above the stated threshold temperature. For example, the time markers for the 10˚C threshold indicator in Duo are calibrated to a temperature of 12˚C/54°F. If the vaccine being monitored breaches its threshold temperature and is held at a constant temperature (i.e. isotherm) of 12˚C, the blue mixture will reach the 3 day print mark within 3 days (+/- 15% in time).

The Accepted Failure Rate is based on ANSI/ASQC Z1.4 (formally MIL-STD-105E) Level II Normal Inspection. For Duo the AQL is 0.65%. Packs are over shipped by 2-3 units per 100 to cover this AQL.
Duo indicators go through extensive quality checks before they are shipped. Central to this process are tests against defined specifications for; run-time accuracy (how quickly the dye progresses through the membrane), environment sensitivity (high heat and vacuum tests to check resilience to harsh conditions during shipping) and also the accuracy of the threshold melting point. A full pack of release reports is provided with each shipment. Further details are available on request.

Yes. The temperature thresholds and time marker specifications can be adjusted. It also possible to change the graphic to incorporate customer colours and logos. All custom orders are subject to a minimum volume and the cost and specification will depend on what is required and feasible. Please contact us for more information.

Yes. Please contact us for the MSDS for further information. We only use food-grade oils and non-toxic colourants in our formulation.

In the unlikely event that the liquid leaks from the indicator and comes into contact with skin, simply wash with soap and water. If the liquid comes into contact with eyes, rinse immediately with plenty of water and seek medical advice.

Contact us today to enquire about Timestrip® PLUS™ samples, samples of multiple products, or general enquiries, please use our contact page.

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