Timestrip PLUS Duo

Double action temperature monitoring in one, cost-effective device
A cumulative breach indicator with readings for excursions above 10°C – in day ranges from 3 to 14, with a secondary indicator to show immediate excursions above an upper temperature breach point of 34°C.

Calibrated to follow WHO recommendations vaccines & medicine
The Timestrip® PLUS Duo provides clear, irreversible visual evidence and distinct time marking of the thermal abuse phase.

In- depth information with push-button simplicity
By removing the ambiguity of temperature abuse across time and temperature thresholds this all-in-one indicator can help prevent the unnecessary wastage of expensive medicines and vaccines..

Timestrip® PLUS Duo
10°C / 50°F 14 Day run-out
34°C / 93°F immediate excursion
Activation confirmation windows
Unique serial number

Timestrip Duo 10 & 34 C
Patented field activation functionality
Highly Accurate
Multi-event dual temperature threshold indicators
Unique serial code printed on each indicator for traceability
Patented field activation functionality
Unambiguous color progression to show length of temperature breach
Displays showing cumulative time of temperature breach
Customized product & carrying cards available
Modern Look & Feel
Environmentally friendly

Our products are manufactured under the controls established by an IQC approved quality management system that conforms with ISO 9001:2008 under certificate number: I7046

Can Timestrips be used in any direction / orientation?
Yes.  Orientation has no impact on the way it works.
What is Duo?
Timestrip® PLUS Duo puts two temperature threshold indicators side by side into one handy label format. The indicator on the left shows if temperatures have breached the cold chain threshold of 10°C/50°F and for how long, with time markers for 3, 8 or 14 days. The indicator on the right shows if temperatures have breached an extreme of 34°C/93°F and for how long, with one time marker for 3 hours. Duo has been engineered to comply with World Health Organisation recommended monitoring requirements for certain vaccines. That is why it combines a threshold indicator of 10°C/50°F with 3, 8, and 14 day time markers and a 34°C/93°F indicator showing 3 hours of breach. However, there is nothing to prevent Duo being used to monitor other products if these time markers and threshold temperatures are suitable. It is also possible to manufacture Dual threshold indicators for other temperature thresholds. (See FAQ on customising Duo).
How does Duo work?
A blue dye housed in a blister is held adjacent to a micro-porous membrane. Upon squeezing the activation button the liquid dye comes out of the blister and into contact with the membrane. If the temperature of the product is below the stated ‘STOP’ temperature, the blue dye changes state to solid form, and it is unable to move through the membrane. If the temperature rises to or above the threshold temperature, the dye changes to liquid form and moves at a precise rate through the membrane. Its progress is irreversible and the distance it travels through the viewing window indicates the cumulative time the indicator has been exposed to the threshold temperature or above. The 10°C and 34°C threshold indicators use different liquid dyes which melt and solidify at different temperatures. The liquid dye in the 10°C blister has a STOP of 8°C/46°F and the liquid dye in the 34°C blister has a STOP of 30°C/86°F.
Do I need to condition Duo prior to activation?
No. Unlike some other threshold temperature products, Duo indicators do not require pre-conditioning. However, you need to activate above the highest threshold temperature, as you cannot squeeze the dye out of the blister if it is in solid form. The temperature of Duo needs to be raised to 35°C/95°F to be able to activate both indicators and then dropped to the lower of the two STOP temperatures (8°C/46°F) to stop the progress of both liquid dyes. The fastest way to do this is by placing Duo in an environment much colder than the STOP temperature (8°C/46°F) for a short period of time.
Any special storage requirements before activation?
No, unlike some other threshold temperature products, they can be held at ambient temperatures.
How accurate is Duo?
+/- 1˚C for each temperature component and +/- 15% for each time component. The run rate of the blue dye across the time markers is calibrated to a temperature of 2˚C above the stated threshold temperature. For example, the time markers for the 10˚C threshold indicator in Duo are calibrated to a temperature of 12˚C/54°F. If the vaccine being monitored breaches its threshold temperature and is held at a constant temperature (i.e. isotherm) of 12˚C, the blue mixture will reach the 3 day print mark within 3 days (+/- 15% in time).
What are your Acceptable Quality Limits?
The Accepted Failure Rate is based on ANSI/ASQC Z1.4 (formally MIL-STD-105E) Level II Normal Inspection. For Duo the AQL is 0.65%. Packs are over shipped by 2-3 units per 100 to cover this AQL. Duo indicators go through extensive quality checks before they are shipped. Central to this process are tests against defined specifications for; run-time accuracy (how quickly the dye progresses through the membrane), environment sensitivity (high heat and vacuum tests to check resilience to harsh conditions during shipping) and also the accuracy of the threshold melting point. A full pack of release reports is provided with each shipment. Further details are available on request.
Can Duo be customised for different time markers and temperature thresholds?
Yes. The temperature thresholds and time marker specifications can be adjusted. It also possible to change the graphic to incorporate customer colours and logos. All custom orders are subject to a minimum volume and the cost and specification will depend on what is required and feasible. Please contact us for more information.
Why does Timestrip give away 1 or 2 free products with every pack of 100?
Because we like our customers! You can use these free products for testing, training, validation, or just to save money. In the unlikely case any got damaged along the way or someone just wanted to try one, there is no need to get in touch, although we're always happy to hear from our customers. Personally, we think that all companies should give stuff away for free!

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Contact us today to enquire about Timestrip PLUS Duo samples. If you would like samples of multiple products, or have a general enquiry, please use our contact page.

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